Continued pages 2....3....4.
Crohn'sCanada
Page 5
Addressing the alarming rise of the bacterium "Mycobacterium avium Paratuberculosis"
in the environment and the growing evidence linking this bacterium to Crohn's
disease.
 

Founders: Diane and Michael Fagen

Contact Info: dianef84@yahoo.com

Home

Our Mission and our Goals

History of Crohn's Disease, Johne's disease, Mycobacterium avium Paratubercuosis

Recent Article Updates

Links to Articles
Page 2....3....4.....5

Perception of Risk

The Precautionary Principle

What is a Reportable Disease

Health of Animals Act, SC 1990, c 21

List of Reportable Diseases and REGULATIONS PRESCRIBING CERTAIN DISEASES AS REPORTABLE DISEASES

NRC National Science Library

Public Health Agency of Canada

Never In My Milk

Links

Messageboard

ree Republic/News Activism/Topics - Post Article

Research

La Presse,  April 8, 2001,  Never in My Milk? by Marie France Coutu

The Canadian Media


Canadian Medical and Government

Canadian Veterinary

Canadian Raw Milk Advocacy Group

 

Let's Talk



 

Taking Action

Link To Us

Does Mycobacterium Paratuberculosis cause Crohn's disease by Alan Kennedy  

(PARA) PARATUBERCULOSIS AWARENESS & RESEARCH ASS.,INC



Shafran's Gasterology Center

The Johne's Information Center

History of Early Research on Crohn's disease

Dr. B. Crohn

Got Milk? by Michael Greger, MD Updated January 2001

THE CROHN'S CONNECTION  by Lisa Chamberlain

Dire Warnings About Johne’s
Disease A wake-up call for the dairy industry?

Micobacteria and Crohn's Disease

Dr. Chiodini's Tables

American and European Links

University of Wisconsin School of Veterinary Medicine

Health Canada

Action Medical Research

 

University of Guelph

NACC

 

 
 
 

PARATUBERCULOSIS AWARENESS

New milk research finds infectious bacteria survives pasteurization

MONDAY, AUGUST 9, 2004, PHOENIX, ARIZONA:.....................In a late-breaking session of the International Association for Food Protection, Dr. Jay Ellingson of the Marshfield Clinic Laboratories, Marshfield, WI, USA presented the Clinic s recent findings that the milk we drink is contaminated with an organism that has been implicated as a suspected cause of Crohn s disease Mycobacterium avium subspecies Paratuberculosis (MAP).............CONTACT: Karen Meyer Cheryl Miller PARA, Inc. (Paratuberculosis Awareness and Research Association) Tel: 813-989-9539 Fax: 813- 987-9559 Email: karen@crohns.org cheryl@crohns.org Website: www.crohns.org

 

Worldnet Daily October 2004

Exclusive Commentary:Crohn's disease, sick cows and contaminated milk: posted: October 1, 2004 1:00 a.m. Eastern By Chris Bennett

 

 

CHRONIC CROHN'S CAMPAIGNE


On The 25TH May 2004 Prof John Hermon Taylor gives a presentation to the huge ASM - American Society of Microbiology Symposium in New Orleans, "It Is the Speech Of His Life" he says.

 

 

Molecular Typing of Mycobacterial Isolates Cultured From The Tissue Of Inflammatory Bowel Disease (Crohn's Disease) Patients by Leanne Adams, B.S. Grove City College, Spring Term 2004

 

 

Goliath April 2004

Unraveling the Mystery of Crohn's Disease Could bacteria found in dairy products play a key role in Crohn's disease? by Patrick Perry

 

  BBC NEWS: April 28, 2004

Farm guidance on Crohn's welcomed Guidelines to farmers is due to be published next month : A man who nearly lost his wife to Crohn's disease is hoping to influence government guidance to farmers. Tim Paige, of Wadhurst, East Sussex, set up Chronic Crohn's Campaign UK eight years ago after Sarah, his wife became ill. After writing to Tony Blair, he took part in research looking at a possible link between Johne's disease, found in dairy herds, and Crohn's disease.
 

THE LANCET: Infectious Diseases: March 4, 2004

Crohn's disease, mycobacteria, and NOD2 Marcel A Behr , Makeda Semret , Audrey Poon , and Erwin Schurr : In a recent Personal view paper, Robert J Greenstein presented the rationale behind efforts to elucidate a mycobacterial cause for Crohn's disease.

 

ClariNews 06-Aug-2003

Bacteria linked to bowel disorder Hermon-Taylor told the BBC he found Mycobacterium avium paratuberculosis bacteria in 92 percent of patients with the disease but only in 26 percent of patients without the condition

 

  THE LANCET Infectious Diseases Vol 3 August 2003 Is Crohn’s disease caused by a mycobacterium? Comparisons with leprosy, tuberculosis, and Johne’s disease
 

August 2003: BBC NEWS

Bacteria linked to bowel disorder Scientists have identified a type of bacteria they believe may cause Crohn's disease

 

 

 

2003: Health Canada: HC0353 Mycobacterium paratuberculosis in Raw Milk : Project Leader: Jeffrey Farber, Health Canada: Bureau of Microbial Hazards, Food Directorate, E-mail: jeff_farber@hc-sc.gc.ca Starting Date : 2003/04 Description: Identifying and managing risks for contamination at source of raw bulk tank milk,
exposure of neonates, and contamination of land and atercourses from high risk animals / farms is of concern to dairy farmers and for the food industry. Although rapid molecular techniques have been developed, their expense and technical challenges (inhibition of Polymerase Chain Reaction) has limited their widespread use and application at farm level. There is a requirement for sensitive, rapid and cost-effective methods for
screening (biological and environmental samples) and detection of live M. paratuberculosis bacterium. This project is funded under the Agricultural Policy Framework and is part of the Research in Support of Standard Setting component.

 

Ontario Dairy Farmer magazine January 2003

Voluntary Johne’s control coming

 

2002: J.Med Microbiology

Crohn's disease caused by Mycobacterium avium subspecies paratuberculosis: a public health tragedy whose resolution is long overdue


Identification of Mycobacterium avium subsp. paratuberculosis in Biopsy Specimens from Patients with Crohn’s Disease Identified by In Situ Hybridization


2002: DIGEST LIVER DIS


Treatment with drugs active against Mycobacterium avium subspecies paratuberculosis can heal Crohn’s disease

 

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Effect of Commercial-Scale High-Temperature, Short-Time Pasteurization on the Viability of Mycobacterium paratuberculosis in Naturally Infected Cows’ Milk

 

November 2002: Science Daily

Scientists Crack Genome Sequence Of Major Dairy Pathogen

 

May 2002: Applied and Environmental Biology


Incidence of Mycobacterium paratuberculosis in Bulk Raw and Commercially Pasteurized Cows' Milk from Approved Dairy Processing Establishments in the United Kingdom Applied and Environmental Biology May 2002

 
 
 

 

Centre for Digestive Diseases

Novel appearance of healing mucosa following anti-Mycobacterium avium paratuberculosis therapy for Crohn's disease

   
 


 

December, 2002: Effect of Pasteurization on Survival of Mycobacterium paratuberculosis in Milk....... A. Gao*, L. Mutharia, S. Chen*, K. Rahn and J. Odumeru* * Laboratory Services Division, University of Guelph, Guelph, Ontario N1H 8J7, Canada Department of Microbiology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada Health Canada, Laboratory for Foodborne Zoonoses, Guelph, Ontario N1G 3W4, Canada

 

 

2002: Effect of Pasteurization on Survival of Mycobacterium paratuberculosis in Milk....... A. Gao*, L. Mutharia, S. Chen*, K. Rahn and J. Odumeru* * Laboratory Services Division, University of Guelph, Guelph, Ontario N1H 8J7, Canada Department of Microbiology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada Health Canada, Laboratory for Foodborne Zoonoses, Guelph, Ontario N1G 3W4, Canada

 

 

JOURNAL OF CLINICAL MICROBIOLOGY 2001

Identification of Mycobacterium avium subsp. paratuberculosis in Biopsy Specimens from Patients with Crohn’s Disease Identified by In Situ Hybridization

 

 

La Presse 2001

Never In My Milk

 

 

CTV News September 2001

Researchers claim to have found a link between bacteria in cow's milk and Crohn's disease. But it appears Ottawa is doing little to ensure milk safety

 

  Paratuberculosis And Crohn's Disease: Got Milk? by Michael Greger, MD Updated January 2001, also full article can be found at http://img2.tapuz.co.il/CommunaFiles/18435731.pdf
 

2001: Crohn's Disease in the UK

Scientists have identified a type of bacteria they believe may cause Crohn's disease. The bowel disorder affects 100,000 Britons and can cause a variety of symptoms, ranging from a lack of appetite to chronic diarrhoea and abdominal pain. Its cause is unknown, although one theory is that it can be passed to humans in milk, suggesting that it may be caused by a bacterium.

 

  July 1998, A needling question: Does Pasteurization really kill M. paratuberculosis. BY KURT GUTKNECHT
 

November 1998: ASCA test is commercially available! In November 1998 issue of American Journal of Gastroenterology under “What's New in GI” R. L. Young reviewed a paper on ASCA marker in Crohn’s disease (1). There has been a surge of papers in the past six months (1-3) confirming that Anti-Saccharomyces cerevisiae mannan antibodies (ASCA) should be considered as a significant diagnostic tool.

 

 

A Review of the Evidence for a Link between Exposure to Mycobacterium Paratuberculosis (MAP)
and Crohn’s Disease (CD) in Humans

 

   
 

2001: ONTARIO, New Directions Research Program, Ministry of Agriculture, Food and Rural Affairs: SR9081 - Mycobacterium Avium Subspecies Paratuberculosis in the Ontario Dairy Industry: Strategies for Detection of the Bacterium in Dairy Products RESEARCHER: Drs. Lucy Mutharia, Dept. of Microbiology and Joseph Odumeru, Laboratory Services Division, UofG

 

 

 

Pubmed 1995: Mycobacterium paratuberculosis and Crohn's disease.

 

Clustering in Crohn's disease Aisenberg J; Janowitz HD Division of Gastroenterology, Mount Sinai School of
Medicine of the City University of New York, New York 10029. J Clin Gastroenterol, 1993 Jul,

 

 

AN IN-DEPTH STUDY OF CROHN’S DISEASE IN TWO FRENCH FAMILIES HJ Van Kruiningen, JF Colombel,
RW Cartun, RH Whitlock, M Koopmans, HO Kangro, JA Hoogkamp-Korstanje, M Lecomte-Houcke, M Devred
and JC Paris; Department of Pathobiology, University of Connecticut, Storrs. Gastroenterology, Vol 104,
351-360, 1993

 

 

 

HEALTH; Baffling Rise of Intestinal Disorder in the Young E-MAIL Print Save Share Del.icio.usDiggFacebook
NewsvinePermalinkBy HAROLD M. SCHMECK JR., SPECIAL TO THE NEW YORK TIMES Published:
December 1, 1988
Reasons for Emergence Evolving ecology and changing human behavior, such as migration, recreation, work,
and culture, influence human exposures to the infectious determinants of chronic as well as acute illnesses
(1,2). Microbial virulence factors, wildlife behavioral traits, zoonotic infections, and the environment all converge
to determine both the infectious capacity of potential pathogens and the likelihood of human exposure.
Superimposed on human genetics and biology, the milieu shapes individual and population risk profiles for the
causal infections agents and their chronic sequelae (7,14,21). Over recent years, the powerful tools of
molecular biology, particularly PCR, plus advances in immunologic and other techniques, have exposed new
causal links by detecting difficult-to-culture and novel agents in chronic disease settings. Microbes can now
be irrefutably linked to pathology without meeting Koch's postulates,
Hill's epidemiologic criteria, or even the
revised criteria of Hill and Evans (22)

 

1987   Journal of Clinical Microbiology:   Crohn's disease-isolated mycobacteria are identical to Mycobacterium paratuberculosis, as determined by DNA probes that distinguish between mycobacterial species. J J McFadden, P D Butcher, R Chiodini and J Hermon-Taylor ABSTRACT

 

GUT 1986: Mycobacterial aetiology of Crohn's disease: serologic study using common mycobacterial antigens and a species-specific glycolipid antigen from Mycobacterium paratuberculosis. S N Cho, P J Brennan, H H Yoshimura, B I Korelitz, D Y Graham Crohn's disease is a granulomatous form of enteritis superficially similar to Johne's disease (paratuberculosis) of ruminants. Recently, a Mycobacterium sp closely related to Mycobacterium paratuberculosis was cultured from tissues of patients with Crohn's disease suggesting that M paratuberculosis may be the aetiologic agent in some cases.

 

Gut March 1986: Occurrence of Crohn's disease in married couples Based on published disease prevalence data and number
of married couples according to the latest census, researchers were able to calculate expected incidence, and
conclude that the number is greater than expected by chance.

 

 

Digestive diseases and Science 1984: Possible role of mycobacteria in inflammatory bowel disease Rodrick J. Chiodini, Herbert J. Van Kruiningen, Walter R. Thayer, Richard S. Merkal and Jessica A. Coutu



Research Received from Doctor John Hermon-Taylor **Please download Adobe Acrobat Reader 5 to read the files below

 

Effect of Commercial-Scale High-Temperature, Short-Time Pasteurization on the Viability of Mycobacterium paratuberculosis in Naturally Infected Cows’ Milk:APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Feb. 2002, p. 602–607 Vol. 68, No. 2 0099-2240/02/$04.000 DOI: 10.1128/AEM.68.2.602–607.2002 Copyright © 2002, American Society for Microbiology. All Rights Reserved.2606/pdf

Identification of Mycobacterium avium subsp. paratuberculosis in Biopsy Specimens from Patients with Crohn’s Disease Identified by In Situ Hybridization. sechi.pdf JOURNAL OF CLINICAL MICROBIOLOGY, 0095-1137/01/$04.000 DOI: 10.1128/JCM.39.12.4514–4517.2001 Dec. 2001, p. 4514–4517 Vol. 39, No. 12 Copyright © 2001, American Society for Microbiology. All Rights Reserved. NOTES

Treatment with drugs active against Mycobacterium avium subspecies paratuberculosis can heal Crohn’s disease: more evidence for a neglected Public Health tragedy J. Hermon-Taylor,DIGEST LIVER DIS 2002;34:9-12 Italcomm .pdf

Crohn's disease caused by Mycobacterium avium subspecies paratuberculosis: a public health tragedy whose resolution is long overdue.J. Med. Microbiol. - Vol. 51 (2002), 3-6 2002 Society for General Microbiology ISSN 0022-2615 EDITORIAL jmedmicro2002.pdf

Incidence of Mycobacterium avium subspecies paratuberculosis in bulk-tank milk samples from different regions in Switzerland electrophoresis of KR products obtained fror different bulk-tank mil samples following the nested IS900 PCR. Lane M 100 by molecular weight ladder (Roche Diagnostics), Lanes 1, and 4 Positive samples with a specific amplification product 298 bp, Lane 3 Negativ sample, +Ko Positive.Swiss.Map.pdf










www.crohnscanada.org ~ MAP-Canada ~ MAP-Canada@crohnscanada.org

Disclaimer:
MAP-Canada does not advocate a particular cause of Crohn's disease.  Our website is intended only to present evidence.  Our readers may draw their own conclusions.  We are not medical specialists and do not offer any treatment or nutritional advice.  Our mission is not to lay blame on any individual or industry, but rather to urge the Government of Canada to address the evidence presented on this site.

Mise au Point:
MAP-Canada ne recommande aucune théorie particulière sur la cause de la maladie de Crohn.L'intente de notre site Web est simplement de présenter certaineévidence mais vous pouvez arriver à vos propres conclusions.Nous ne pouvons donner de conseils de nature médicale ou alimentaire. Notre mission ne consiste aucunement à blâmer un individuou une industrie mais
plutôt à s'assurer que le Gouvernement du Canada aborde l'évidence que nous présenton

MAP-Canada would like to extend a very sincere thank you to Yanik Chicoine at www.mirweb.com for his generosity and assistance in the hosting and the mounting of this site.

MAP-Canada aimerait remercier sincèrement Yanik Chicoine a www.mirweb.com pour sons générosité et sons assistance pour l'hébergement et la programation du site.



Continued pages 2....3....4.